Coercing bisphosphonates to kill cancer cells with nanoscale coordination polymers.

نویسندگان

  • Demin Liu
  • Stephanie A Kramer
  • Rachel C Huxford-Phillips
  • Shunzhi Wang
  • Joseph Della Rocca
  • Wenbin Lin
چکیده

Nanoscale coordination polymers containing exceptionally high loadings of bisphosphonates were coated with single lipid bilayers to control the drug release kinetics and functionalized with a targeting ligand to endow cell-targeting capability, leading to much enhanced cytotoxicity against human lung and pancreatic cancer cells.

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عنوان ژورنال:
  • Chemical communications

دوره 48 21  شماره 

صفحات  -

تاریخ انتشار 2012